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課程名稱 |
臨床影像及神經影像二
Clinical Imaging & Neurological Imaging(Ⅱ) |
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開課學期 |
107-2 |
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授課對象 |
學程 神經生物與認知科學學程 |
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授課教師 |
湯佩芳 |
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課號 |
PT8058 |
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課程識別碼 |
428 D0530 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三8,9(15:30~17:20) |
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上課地點 |
討論室一 |
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備註 |
與吳瑞美、邱銘章、鄭建興、彭信逢、陳雅芳、賴達明、湯頌君、曾文毅合授
限博士班 且 限本系所學生(含輔系、雙修生)
總人數上限：5人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1072PT8058_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
本課程目的為培育物理治療師判讀神經、血管影像的能力，以及運用神經、血管影像於物理治療臨床決策與臨床研究的能力。課程內容以介紹腦與脊髓系統之神經、血管影像為主，含：影像成像原理之介紹，正常與異常之影像判讀，以及影像如何應用於主要神經疾患(如腦中風、巴金森氏症、失智症、腦瘤、頭部外傷、水腦、脊髓損傷與病變等)之診斷、預後、治療、及研究。課程之進行採用授課、課堂討論、文獻閱讀、與個案報告並行的方式。為達最佳之學習效果，請修習學生務必事先預習每次上課的參考文獻或資料。本課程之設計涵蓋培養學生之專業與教學能力、跨領域團隊合作與領導、及創新與研究等核心能力。 |
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課程目標 |
修習學生在結束本課程時，應能：
1. 瞭解電腦斷層、磁振造影、磁振血管攝影、正子攝影、與神經超音波等之影像原理；
2. 學習判讀腦與脊髓系統的神經與血管影像；
3. 瞭解神經、血管影像判讀結果與臨床表徵間的關係；
4. 學習應用神經、血管影像資訊於神經物理治療主要臨床疾病類別之功能性診斷、預後、與治療臨床決策。 |
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課程要求 |
期中口頭與書面報告:
以FLAIR MRI, atlas, and brain slices 找出與executive functions, sensorimotor function, visual processing and perception, emotion, and memory function 相關之腦區。
期末口頭與書面報告:
以一種神經疾患之一位個案作個案研究(case study)，完整報告個案之神經、血管 影像、診斷、臨床症狀與問題、預後、醫學處理(medical management)過程、物理治療介入(physical therapy intervention)過程、與介入後之結果(outcomes)。 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
I. Neuroanatomy textbooks
A. Haines DE. Neuroanatomy: An atlas of structures, sections, and systems. 9th Ed. Philadelphia: Wolters Kluwer. 2015.
B. Kiernan JA, Rajakumar N. Barr’s The Human Nervous System: An anatomical Viewpoint. 10th Ed. Philadelphia: Wolters
Kluwer Lippincott Williams & Wilkins, 2014.
C. Mai JK and Paxinos G. The human nervous system [electronic resource]. 3rd Ed. Burlington: Elsevier Science, 2011
D. Mai JK, Paxinos G, Voss T. Atlas of the human brain. 3rd Ed. New York: Academic Press. 2008.
E. Vanderah, TW. Nolte’s the Human Brain: An Introduction to Its Functional Anatomy [electronic resource]. 7th ed.
Philadelphia, PA: Elsevier. 2016.
II.Neuroscience textbooks
A. Bear M, Connors B, Paradiso M. Neuroscience: Exploring the brain, 3 ed. Baltimore: Lippincott Williams & Wilkins. 2016.
B. Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia A-W, White LE. Editors. Neuroscience. 5th Ed. Sunderland, MA,
USA: Sinaur Associates, Inc. 2012.
C. Lundy-Ekman L. Neuroscience Fundamentals for Rehabilitation. 4rd ed. St. Louis: Saunders Elsevier; 2013
III. Neuroimaging textbooks
A. Gillard JH, Waldman AD, and Barker PB. Clinical MR neuroimaging: Physiological and functional techniques (2nd ed). New
York: Cambridge University Press. 2010.
B. Naidich TP. Duvernoy's atlas of the human brain stem and cerebellum [electronic resource]: High-field MRI: Surface
anatomy, internal structure, vascularization and 3D sectional anatomy. Vienna: Springer Vienna. 2009.
C. Sanelli PC et al. Neuroimaging: the essentials. Philadelphia: Wolters Kluwer. 2016.D. Scott W. Atlas (Editor). Magnetic
resonance imaging of the brain and spine [electronic resource]. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2017.
E. Scott W. Atlas (Editor) MRI of the brain and spine [electronic resource]. Philadelphia: Lippincott Williams & Wilkins.
2008.
F. Talairach, J. Co-planar stereotaxic atlas of the human brain: 3-dimensional proportional system: An approach to medical
cerebral imaging. NY: Thieme Medical Publishers.
G. Westbrook C, Roth CK, TalbotJ. MRI in practice (4th ed). Chichester, West Sussex; Malden, MA: Wiley-Blackwell. 2011.4
H. Westbrook C. MRI at a glance (2nd ed). Chichester, U.K. ; Malden, MA: Wiley-Blackwell. 2010.
I. 陳煥武編譯(Catherine Westbrook 原著)。圖解核磁共振造影學。台北市:合記。2006。
IV. Other readings: to be determined by instructors
A. Basic principles of imaging
1. Goldman LW. Principles of CT and CT technology. J Nucl Med Technol 2007;35:115-128; quiz 129-130.
2. Currie S, Hoggard N, Craven IJ, Hadjivassiliou M, Wilkinson ID. Understanding MRI: basic MR physics for physicians.
Postgrad Med J 2013;89:209-223.
3. Townsend DW. Physical principles and technology of clinical PET imaging. Ann Acad Med Singapore 2004;33:133-145.
B. Stroke
1. Bivard A, Spratt N, Miteff F, Levi C, Parsons MW. Tissue Is More Important than Time in Stroke Patients Being Assessed
for Thrombolysis. Frontiers in neurology 2018;9:41.
2. Campbell BC, Parsons MW. Imaging selection for acute stroke intervention. Int J Stroke 2018;13:554-567.
3. Tsivgoulis G, Katsanos AH, Schellinger PD, et al. Advanced Neuroimaging in Stroke Patient Selection for Mechanical
Thrombectomy. Stroke 2018;49:3067-3070.
4. Vilela P, Rowley HA. Brain ischemia: CT and MRI techniques in acute ischemic stroke. Eur J Radiol 2017;96:162-172.
V. Other electronic resources
A. de Asis Bravo-Rodriguez F, Diaz-Aguilera R. Hygino Cruz Jr. LC. (Editors) Learning neuroimaging [electronic resource]:
100 essential cases. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. 2012.
B. Espinosa PS, Smith CD. Neurology Self-Assessment: Focus on Neuroimaging [electronic resource]. Philadelphia: Lippincott
Williams & Wilkins. 2009. (叢書名 Neurology self-assessment)
C. Barkovich AJ, Raybaud C. Pediatric neuroimaging [electronic resource]. Philadelphia: Wolters Kluwer Health/Lippincott
Williams & Wilkins. 2012.
D. Barkhof F. et al. Neuroimaging in dementia [electronic resource]. Berlin, Heidelberg : Springer-Verlag Berlin
Heidelberg. 2011. |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
上課參與、報告、及討論 |
20% |
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2. |
期中口頭與書面報告 |
30% |
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3. |
期末口頭報告 |
25% |
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4. |
期末書面報告 |
25% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/20 |
Course overview
Review of brain and spinal cord anatomy |
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第2週 |
2/27 |
Brain anatomy: Atlas and FLAIR MRI |
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第3週 |
3/06 |
Brain anatomy: Brain Slices (Lab) |
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第4週 |
3/13 |
Brain anatomy: Brain Slices (Lab) |
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第5週 |
3/20 |
Introduction to basic principles of CT, MRI, and PET |
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第6週 |
3/27 |
CT and MRI images of the adult brain and spinal cord: Guides for reading normal and pathological images |
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第7週 |
4/03 |
溫書假 |
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第8週 |
4/10 |
CT and MRI images of the adult brain and spinal cord: Neuroimage correlates of clinical S/S: Cases |
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第9週 |
4/17 |
期中報告(by individual) |
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第10週 |
4/24 |
Pediatric neuroimaging |
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第11週 |
5/01 |
Ultrasonic imaging in neurological disorders |
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第12週 |
5/08 |
Neuroimaging in stroke- I.學生文獻報告(by group) |
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第13週 |
5/15 |
Neuroimaging in stroke- II. Hyperacute, acute,
subacute, and chronic ischemic stroke |
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第14週 |
5/22 |
Neuroimaging in cerebral hemorrhage, hydrocephalus,brain tumor, and traumatic brain injury |
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第15週 |
5/29 |
Neuroimaging in spinal disorders |
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第16週 |
6/05 |
Neuroimaging in Parkinson’s disease and other basal ganglia disorders |
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第17週 |
6/12 |
Neuroimaging in dementia |
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第18週 |
6/19 |
期末報告– case study reports (by individual) |
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